Product Description

NBN Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4582-25, MB4582-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Monkey

Host: Mouse

Applications: 10k-ChIP, IF, IHC, WB

Alternate Names: AT-V1, AT-V2, ATV, NBS, NBS1, P95

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Human recombinant protein fragment corresponding to amino acids 461-754 of human NBN (NP_002476) produced in E.coli.

Dilution: IHC 1:100, IF 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: 84.8 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60934

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only