NBN Polyclonal Antibody - E-AB-62135

NBN Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-62135-60, E-AB-62135-120, E-AB-62135-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NBN

Target Synonym: NBN; AT-V1; AT-V2; ATV; NBS; NBS1; P95; nibrin

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O60934

Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human NBN

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only