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NBPF12 Polyclonal Antibody - BS61787

NBPF12 Polyclonal Antibody - BS61787

Regular price $274.50 CAD
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NBPF12 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61787-50, BS61787-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, cognitive disability, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene family contains numerous pseudogenes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Neuroblastoma breakpoint family member 12, Chromosome 1 amplified sequence 1, NBPF12, COAS1, KIAA1245, Neuroblastoma breakpoint family member 10, NBPF10, Neuroblastoma breakpoint family member 15, Neuroblastoma breakpoint family member 16, NBPF15, NBPF16, Neuroblastoma breakpoint family member 1, NBPF1, KIAA1693, Neuroblastoma breakpoint family member 9, NBPF9, Neuroblastoma breakpoint family member 20, NBPF20, Neuroblastoma breakpoint family member 14, NBPF14

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human NBPF12.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NBPF12 Polyclonal Antibody detects endogenous levels of NBPF12 protein.

Molecular Weight: ~ 99-140 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q5TAG4/Q6P3W6/Q5SXJ2/Q3BBV0/Q3BBW0/Q3BBV1/Q8N660/Q5TI25

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only

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