NBR1 Rabbit Polyclonal Antibody - BT-AP11720

NBR1 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11720-20, BT-AP11720-50, BT-AP11720-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.

Research Areas: Cell biology

Target Protein: NBR1

Applications: IHC-p, IF

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Next to BRCA1 gene 1 protein

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q14596; Mouse: P97432; Rat: Q501R9

Synonyms: Next to BRCA1 gene 1 protein;Cell migration-inducing gene 19 protein;Membrane component chromosome 17 surface marker 2;Neighbor of BRCA1 gene 1 protein;Protein 1A1-3B; Next to BRCA1 gene 1 protein; Cell migration-inducing gene 19 protein; Membrane component chromosome 17 surface marker 2; Neighbor of BRCA1 gene 1 protein; Protein 1A1-3B

GeneID: Human: 4077

Research Use Only