NCAM-L1 Monoclonal Antibody
Size: 50μL, 100μL
Catalogue Numbers: RA11734-50, RA11734-100
Citations, Manuals and MSDS Available upon request.
Background: L1 cell adhesion molecule (L1CAM) Homo sapiens The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013],
Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Storage Instructions: -20°C/1 year
Applications: WB
Species Cross-Reactivity: Human; Mouse; Rat; Dog; Rabbit
GeneID (Human): 3897
SWISS: P32004
Source: Mouse
Research Use Only