Product Description

NCAM-L1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11734-50, RA11734-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: L1 cell adhesion molecule (L1CAM) Homo sapiens The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013],

Reactivity: Human, Mouse, Rat, Dog, Rabbit

Host: Mouse

Applications: WB

Alternate Names: L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CD antigen CD171

Clonality: Monoclonal

Dilution: Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Human Gene ID: 3897

Research Use Only