Product Description

NCAM-L1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27612-50, RA27612-100

Citations, Manuals and MSDS Available upon request.

Background: L1 cell adhesion molecule (L1CAM) Homo sapiens The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus) . Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000

Alternative Names: Neural cell adhesion molecule L1 (N-CAM-L1;NCAM-L1;CD antigen CD171)

Applications: IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3897

SWISS: P32004

Source: Rabbit

Research Use Only