NCAPH2 Monoclonal Antibody-MB11268

NCAPH2 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11268-50, MB11268-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q6IBW4

Host: Rabbit

Reactivity: Human

Applications: WB,IHC-F,IHC-P,ICC/IF,IP

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (PubMed:14532007). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size . Seems to have lineage-specific role in T-cell development (PubMed:14532007).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of NCAPH2 in Hela, JurkatLysates using NCAPH2 antibody.

Bioworld Molecular Weight: Calculated MW: 68 kDa; Observed MW: 68 kDa

Specificity: IgG

Alternative Name: CAPH2

Immunogen: A synthetic peptide of human NCAPH2

Conjugate: Unconjugated

Modification: Unmodified