NCF1C rabbit pAb - ES14543

NCF1C rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14543-50, ES14543-100

Citations, Manuals and MSDS Available upon request.

Background: The neutrophil cytosolic factor 1 (NCF1) gene encodes the 47 kDa cytosolic subunit of neutrophil NADPH oxidase, which produces superoxide anion. The NCF1 gene is located in close proximity to two highly similar, multi-exon pseudogenes at chromosome 7q11.23, corresponding to this gene record and GeneID:654816. The two pseudogenes contain a dinucleotide deletion (delta-GT) in exon 2 that results in a frameshift and truncation of the open reading frame, and neither pseudogene is likely to express a protein. Recombination events between the pseudogenes and the functional NCF1 gene can inactivate the NCF1 gene and result in chronic granulomatous disease. [provided by RefSeq, Nov 2009],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human NCF1C AA range: 100-150

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human SWISS Prot NO: A8MVU1

Subcellular Location: Cytoplasm

Research Use Only