Product Description

ND6 Polyclonal Antibody

Catalogue Numbers: BS1632-50, BS1632-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P03925

Host: Rabbit

Reactivity: Mouse

Applications: WB

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by translocation of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. The significance of NADH dehydrogenase subunit 6 (ND6) is rapidly becoming increasingly apparent as many mutations leading to amino acid changes in this subunit are associated with known mitochondrial diseases.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ND6 polyclonal antibody detects endogenous levels of ND6 protein.

Extra Notes: Western blot (WB) analysis of ND6 polyclonal antibody at 1:1000 dilution
Lane1:The muscle tissue lysate of Mouse (47μg)

Bioworld Molecular Weight: ~ 19 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: NADH-ubiquinone oxidoreductase chain 6 (EC:1.6.5.3); NADH dehydrogenase subunit 6; Mtnd6; mt-Nd6; Nd6

Immunogen: A synthetic peptide corresponding to amino acids 72-86 of Mouse ND6.

Conjugate: Unconjugated

Modification: Unmodified