NDRG1 Polyclonal Antibody - BT-AP11748

NDRG1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11748-20, BT-AP11748-50, BT-AP11748-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Areas: Cancer; Epigenetics and nuclear signaling; Neuroscience

Target Protein: NDRG1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Protein NDRG1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q92597; Mouse: Q62433; Rat: Q6JE36

Synonyms: Protein NDRG1;Differentiation-related gene 1 protein;DRG-1;N-myc downstream-regulated gene 1 protein;Nickel-specific induction protein Cap43;Reducing agents and tunicamycin-responsive protein

GeneID: Human: 10397

Research Use Only