NDUFA1 Polyclona Antibody - RA27640

NDUFA1 Polyclona Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA27640-50, RA27640-100 Citations, Manuals and MSDS Available upon request. Background: NADH:ubiquinone oxidoreductase subunit A1 (NDUFA1) Homo sapiens The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: IHC-p 1:50-200, ELISA (peptide) 1:5000-20000 Alternative Names: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE;CI-MWFE;NADH-ubiquinone oxidoreductase MWFE subunit) Applications: IHC; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 4694 SWISS: O15239 Source: Rabbit Research Use Only