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NDUFS2 Polyclonal Antibody - E-AB-16636

NDUFS2 Polyclonal Antibody - E-AB-16636

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NDUFS2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-16636-60, E-AB-16636-120, E-AB-16636-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NDUFS2

Target Synonym: CI 49; CI 49kD; CI-49kD; Complex 1; mitochondrial respiratory chain; 49 KD subunit; Complex I 49kD; Complex I 49kDa subunit; Complex I-49kD; mitochondrial; NADH dehydrogenase (ubiquinone) Fe S protein 2 49kDa; NADH dehydrogenase (ubiquinone) Fe S protein 2; 49kDa (NADH coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron sulfur protein 2; mitochondrial; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2; NADH ubiquinone oxidoreductase 49 kDa subunit; NADH ubiquinone oxidoreductase NDUFS2 subunit; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH:ubiquinone oxidoreductase core subunit S2; Ndufs2; NDUS2

Research Areas: Cancer, Cell biology, Metabolism, Signal transduction, Tags and Cell markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O75306

Background: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.7 mg/mL

Immunogen: Synthetic peptide of human NDUFS2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Calculated MW: 53kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only