NDUS2 Polyclonal Antibody - BT-AP11781

NDUS2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11781-20, BT-AP11781-50, BT-AP11781-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Cell biology; Metabolism; Signal transduction; Tags and cell markers

Target Protein: NDUFS2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O75306; Mouse: Q91WD5; Rat: Q641Y2

Synonyms: NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial;EC 1.6.5.3;EC 1.6.99.3;Complex I-49kD;CI-49kD;NADH-ubiquinone oxidoreductase 49 kDa subunit

GeneID: Human: 4720

Research Use Only