Nectin 3 rabbit pAb - ES3991

Nectin 3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3991-50, ES3991-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],

Alternate Name: PVRL3; PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL3. AA range:311-360

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 25945

Human SWISS Prot NO: Q9NQS3

Subcellular Location: Cell membrane; Single-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane.

Research Use Only