NEDL2 rabbit pAb - ES6915

NEDL2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6915-50, ES6915-100

Citations, Manuals and MSDS Available upon request.

Background: function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 C2 domain., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 2 WW domains., subunit:Interacts with TP73., tissue specificity:Predominantly expressed in adult brain, lung and heart.,

Alternate Name: HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 140-150kD

Human Gene ID: 57520

Human SWISS Prot NO: Q9P2P5

Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, spindle.

Research Use Only