NEK3 Polyclonal Antibody - BT-AP11800

NEK3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11800-20, BT-AP11800-50, BT-AP11800-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cancer; Signal transduction

Target Protein: NEK3

Applications: WB, ELISA

Reactivity: Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Serine/threonine-protein kinase Nek3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P51956; Mouse: Q9R0A5

Synonyms: Serine/threonine-protein kinase Nek3;EC 2.7.11.1;HSPK 36;Never in mitosis A-related kinase 3;NimA-related protein kinase 3

GeneID: Human: 4752

Research Use Only