NEK7 Rabbit Monoclonal Antibody-MB66368

NEK7 Rabbit Monoclonal Antibody

Catalogue Numbers: MB66368-50, MB66368-100

Sizes: 50µl, 100µl

Product: Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Swiss-Prot: Q9ES74/D3ZBE5

Host: Rabbit

Reactivity: Mouse, Rat

Applications: WB, IP

All Applications: WB (1/500 - 1/1000), IP (1/10 - 1/50)

Background: NIMA was originally shown in Aspergillus nidulans to be necessary for entry into mitosis. NIMA-related mammalian proteins have since been identified as Nek1-4 and Nek6-9. High expression of Nek1 is seen in male and female germ cell lines of mice. Nek2 is the closest known mammalian relative to NIMA. Like NIMA, Nek2 expression peaks at the G2 to M phase transition.Nek3, Nek6, Nek7 and Nek9 also regulate mitosis. Nek1 and Nek8 have been linked with polycystic kidney disease, and Nek4 expression is present in most primary carcinomas. Nek7 localizes to the cytoplasm and is highly expressed in lung, testis, muscle, slpeen, heart, liver, leukocyte and brain. Lower expression of Nek7 is detected in the ovary, prostate and kidney, while no expression is seen in small intestine.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of NEK7 protein.

Extra Notes: Western blot analysis of NEK7 expression in NIH3T3 (A), Raw264.7 (B), rat brain (C), C6 (D) whole cell lysates.

Bioworld Molecular Weight: ~ 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Serine/threonine-protein kinase Nek7; Never in mitosis A-related kinase 7; NimA-related protein kinase 7

Immunogen: A synthetic peptide of human NEK7

Conjugate: Unconjugated

Modification: Unmodified