Product Description

NEK7 Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66368-50, MB66368-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: NIMA was originally shown in Aspergillus nidμlans to be necessary for entry into mitosis. NIMA-related mammalian proteins have since been identified as Nek1-4 and Nek6-9. High expression of Nek1 is seen in male and female germ cell lines of mice. Nek2 is the closest known mammalian relative to NIMA. Like NIMA, Nek2 expression peaks at the G2 to M phase transition.Nek3, Nek6, Nek7 and Nek9 also regμlate mitosis. Nek1 and Nek8 have been linked with polycystic kidney disease, and Nek4 expression is present in most primary carcinomas. Nek7 localizes to the cytoplasm and is highly expressed in lung, testis, muscle, slpeen, heart, liver, leukocyte and brain. Lower expression of Nek7 is detected in the ovary, prostate and kidney, while no expression is seen in small intestine.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB, IP

Alternate Names: Serine/threonine-protein kinase Nek7, Never in mitosis A-related kinase 7, NimA-related protein kinase 7

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human NEK7

Dilution: WB (1/500 - 1/1000), IP (1/10 - 1/50)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of NEK7 protein.

Molecular Weight: ~ 35 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9ES74/D3ZBE5

Product: Liquid in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Research Use Only