Nephrocystin-4 Polyclonal Antibody - BT-AP05889

Nephrocystin-4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05889-20, BT-AP05889-50, BT-AP05889-100

Citations, Manuals and MSDS Available upon request.

Background: NPHP4 encodes a protein involved in renal tubular development and function. Nephrocystin-4 interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

Research Areas: Others

Target Protein: NPHP4

Applications: IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Nephrocystin-4 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 157598

UniProt Accession: Human: O75161; Mouse: P59240

Synonyms: NPHP4; KIAA0673; Nephrocystin-4; Nephroretinin

GeneID: Human: 261734

Research Use Only