Nesprin-3 Polyclonal Antibody - BT-AP05891

Nesprin-3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05891-20, BT-AP05891-50, BT-AP05891-100

Citations, Manuals and MSDS Available upon request.

Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

Research Areas: Signal Transduction

Target Protein: SYNE3

Applications: WB, IF, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Nesprin-3 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 112216

UniProt Accession: Human: Q6ZMZ3; Mouse: Q4FZC9

Synonyms: SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3

GeneID: Human: 161176; Mouse: 212073

Research Use Only