Nesprin-3 rabbit pAb - ES4963

Nesprin-3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4963-50, ES4963-100

Citations, Manuals and MSDS Available upon request.

Background: function:Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which theters the nucleus to the cytoskeleton by binding PLEC1/Plectin which can associate with the intermediate filament system., similarity:Belongs to the nesprin family., similarity:Contains 1 KASH domain., similarity:Contains 2 spectrin repeats., subcellular location:Located at the rough reticulum endoplasmic (RER) in some cells., subunit:Interacts with actin-binding domain of PLEC1/plectin.,

Alternate Name: SYNE3; C14orf49; Nesprin-3; Nuclear envelope spectrin repeat protein 3

Source: Rabbit

Applications: WB; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human C14orf49. AA range:169-218

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 115kD

Human Gene ID: 161176

Human SWISS Prot NO: Q6ZMZ3

Subcellular Location: Nucleus outer membrane; Single-pass type IV membrane protein. Nucleus envelope. Rough endoplasmic reticulum.

Research Use Only