Product Description

Netrin-1 (Q533) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3569-50, BS3569-100

Sizes: 50µl, 100µl

Swiss-Prot: O95631

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: Netrin-G1 ligand (NGL1) is a transmembrane protein containing leucine-rich repeat (LRR) and immunoglobulin (Ig) domains that specifically interact with netrin-G1 through its LRR region. Whereas netrin-G1 is expressed highly in mouse thalamic axons, NGL1 is most abundant in the striatum and the cerebral cortex. NGL1 is implicated in facilitating axonal growth of the vertebrate CNS. Membrane-bound netrin-G1 acts as an axonal receptor, whereas the LRR-containing transmembrane protein NGL1 acts as a ligand in promoting the growth of thalamic axons.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Netrin-1 (Q533) polyclonal antibody detects endogenous levels of Netrin-1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Netrin-1 (Q533) pAb in paraffin-embedded human liver carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 68 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Netrin-1; Epididymis tissue protein Li 131P; NTN1L; NTN1

Immunogen: Synthetic peptide, corresponding to amino acids 501-550 of Human Netrin-1.

Conjugate: Unconjugated

Modification: Unmodified