NEUG rabbit pAb - ES14520

NEUG rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14520-50, ES14520-100

Citations, Manuals and MSDS Available upon request.

Background: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1: 50-200

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human NEUG AA range: 23-73

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4900

Human SWISS Prot NO: Q92686

Subcellular Location: nucleus, trans-rk transport vesicle membrane, postsynaptic density, axon, mitochondrial membrane, neuronal cell body, dendritic spine head,

Research Use Only