Neurexin IIIβ rabbit pAb - ES8028

Neurexin IIIβ rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8028-50, ES8028-100

Citations, Manuals and MSDS Available upon request.

Background: NRXN3 (neurexin 3) encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.

Alternate Name: NRXN3; KIAA0743; Neurexin-3-beta; Neurexin III-beta

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from Neurexin IIIβ . at AA range: 30-110

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 70kD

Human Gene ID: 9369

Human SWISS Prot NO: Q9HDB5

Subcellular Location: Membrane; Single-pass type I membrane protein.

Research Use Only