Product Description

Neuro D2 (D94) Polyclonal Antibody

Catalogue Numbers:BS2316-50, BS2316-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15784

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Neuro D2 (neurogenic differentiation 2), also known as NDRF, NEUROD2 or bHLHa1, is a 382 amino acid nuclear protein that contains one bHLH domain and functions to induce neurogenic differentiation, playing an important role in the maintenance and determination of cell fate.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 48 kDa

Specificity: Neuro D2 (D94) polyclonal antibody detects endogenous levels of Neuro D2 protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: bHLHa1; Class A basic helix-loop-helix protein 1; NDF2; NDR2; NDRF; NeuroD-related factor; NeuroD2;

Immunogen: Synthetic peptide, corresponding to amino acids 62-118 of Human Neuro D2.

Conjugate: Unconjugated

Modification: Unmodified