Neurocalcin δ rabbit pAb - ES7722

Neurocalcin δ rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7722-50, ES7722-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008],

Alternate Name: NCALD; Neurocalcin-delta

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from Neurocalcin δ . at AA range: 370-450

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 83988

Human SWISS Prot NO: P61601

Subcellular Location: intracellular, cytosol, clathrin coat of trans-Golgi network vesicle, extracellular exosome,

Research Use Only