Neurofibromin Polyclonal Antibody - BT-AP05927

Neurofibromin Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP05927-20, BT-AP05927-50, BT-AP05927-100

Citations, Manuals and MSDS Available upon request.

Background: NF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Research Areas: Neuroscience

Target Protein: NF1

Applications: WB, IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Neurofibromin Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 319372

UniProt Accession: Human: P21359; Mouse: Q04690; Rat: P97526

Synonyms: NF1; Neurofibromin; Neurofibromatosis-related protein NF-1

GeneID: Human: 4763; Mouse: 18015; Rat: 24592

Research Use Only