Neuropilin-1 (NRP1) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A16697-20, A16697-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 103kDa
Observed Molecular Weight: 120kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 8829
SWISS: O14786
Alternate Names: NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1 (NRP1)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, CDs, Neuroscience, Stem Cells, Cardiovascular, Angiogenesis.
NCBI Alias: NRP1
Research Use Only