Neuropilin-1 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS90932-50, BS90932-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: O14786(Human) P97333(Mouse) Q9QWJ9(Rat)
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, ICC/IF, IHC, IP, , FC
All Applications: WB:1:1,000-1:5,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100
Background: Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Neuropilin-1 polyclonal antibody detects endogenous levels of Neuropilin-1 protein.
Bioworld Molecular Weight: 120 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Neuropilin-1 on different lysates using anti-Neuropilin-1 antibody at 1/1,000 dilution.
Positive control:
Lane 1: Mouse heart
Lane 2: Mouse liver
Lane 3: Mouse kidney
Lane 4: Human liver, ICC staining Neuropilin-1 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Alternative Name: NRP1, NRP, VEGF165R, A5 protein, BDCA4, BLOOD DENDRITIC CELL ANTIGEN 4, CD304, Neuropilin-1, Neuropilin1, NP1, NPN1, NRP 1, NRP, NRP1, NRP1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified