Neuropilin 1 Rabbit Monoclonal Antibody -BS40088

Neuropilin 1 Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40088-50, BS40088-100

Swiss-Prot: O14786

Host: Rabbit

Neuropilin 1 Rabbit Monoclonal Antibody -BS40088

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP, FC

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.

Purification and Purity: Affinity-chromatography

Specificity: Neuropilin 1 Antibody detects endogenous levels of total Neuropilin 1

Bioworld Molecular Weight: ~ 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Neuropilin 1 Rabbit monoclonal antibody at 1:500 dilution
Lane 1: PC12 whole cell lysate (30ug)
Lane 2: 3T3-L1 whole cell lysate (30ug)
Lane 3: A549 whole cell lysate (30ug), Immunohistochemical analysis of paraffin-embedded human melanoma, using Neuropilin 1 Antibody.

Alternative Name: A5 protein; BDCA4; CD304Neuropilin1; NP1; NPN1; NRP1; VEGF165RNEL like protein 1; Blood dendritic cell antigen 4

Immunogen: A synthesized peptide derived from human Neuropilin 1

Modification: Unmodified

Conjugate: Unconjugated