NF-E4 rabbit pAb - ES14508

NF-E4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14508-50, ES14508-100

Citations, Manuals and MSDS Available upon request.

Background: The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

Alternate Name: Transcription factor NF-E4

Source: Rabbit

Applications: IHC; IF; WB

Dilution: IHC-p 1:50-200, WB 1:500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human NF-E4

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 19kD

Human Gene ID: 58160

Human SWISS Prot NO: Q86UQ8

Subcellular Location: Nucleus

Research Use Only