NFAT4 (E159) Polyclonal Antibody-BS1559

NFAT4 (E159) Polyclonal Antibody

Catalogue Numbers:BS1559-50, BS1559-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q12968

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 115 kDa

Specificity: NFAT4 (E159) polyclonal antibody detects endogenous levels of NFAT4 protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Nuclear factor of activated T-cells; cytoplasmic 3; NF-ATc3; NFATc3; NFATx; T-cell transcription factor NFAT4; NF-AT4; NFAT4; NFATC3

Immunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human NFAT4.

Conjugate: Unconjugated

Modification: Unmodified