NFATC2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A3107-20, A3107-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 100kDa
Observed Molecular Weight: 140kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 4773
SWISS: Q13469
Alternate Names: JCOSL; NFAT1; NFATP; NFATC2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 IF-P, 1:50 - 1:200 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Signal Transduction, Endocrine Metabolism, Immunology Inflammation, B Cell Receptor Signaling Pathway, T Cell Receptor Signaling Pathway, Cardiovascular, Hypoxia, Heart, Hypertrophy.
NCBI Alias: NFATC2
Research Use Only