NFATC2IP Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-91450-60, E-AB-91450-120, E-AB-91450-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: NFATC2IP
Target Synonym: NFATC2IP; ESC2; NIP45; RAD60
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q8NCF5
Background: In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human NFATC2IP
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 13kDa/15kDa/45kDa
Observed MW: 45kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only