NFE2 Polyclonal Antibody - BT-AP09118

NFE2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP09118-20, BT-AP09118-50, BT-AP09118-100

Citations, Manuals and MSDS Available upon request.

Background: Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis| heme synthesis| and the procurement of iron.|Belongs to the bZIP family.|Belongs to the bZIP family. CNC subfamily.|Contains 1 bZIP domain.|subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis.|tissue specificity:Expressed in hematopoietic cells and also in colon and testis.|

Research Areas: Epigenetics and nuclear signaling

Target Protein: NFE2

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Transcription factor NF-E2 45 kDa subunit

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q16621; Mouse: Q07279; Rat: Q6AYT2

Synonyms: Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2;Nuclear factor; erythroid-derived 2 45 kDa subunit;p45 NF-E2)

GeneID: Human: 4778

Research Use Only