NFE2 rabbit pAb - ES10767

NFE2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES10767-50, ES10767-100

Citations, Manuals and MSDS Available upon request.

Background: function:Required for activity at the locus control region (LCR) upstream of the globin gene complexes. Requires p18 NF-E2 for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production: globin synthesis, heme synthesis, and the procurement of iron., similarity:Belongs to the bZIP family., similarity:Belongs to the bZIP family. CNC subfamily., similarity:Contains 1 bZIP domain., subunit:Interacts with MLL2; leading to activate transcription of the beta-globin locus (By similarity). Heterodimer of p45 NF-E2 and p18 NF-E2. Forms high affinity heterodimer with MAFG; the interaction promotes erythropoiesis., tissue specificity:Expressed in hematopoietic cells and also in colon and testis.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 41kD

Human Gene ID: 4778

Human SWISS Prot NO: Q16621

Subcellular Location: Nucleus, PML body. Cytoplasm. The sumoylated form locates to the nuclear bodies PML oncogenic domains (PODs). Translocated to the cytoplasm through interaction with ITCH.

Research Use Only