Product Description

NFkB-p65 (phospho-S536) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5088-50, BS5088-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IHC

Alternate Names: p65, p65 NF kappaB, p65 NFkB, RELA, NFKB P65, Transcription Factor p65, Nuclear factor NF-kappa-B p65 subunit, NFkB-p65, NFKB3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: p-NFkB-p65 (S536) polyclonal antibody detects endogenous levels of NFkB-p65 protein only when phosphorylated at Ser536.

Molecular Weight: ~ 60, 75 kDa

Pathway: NF-kB Signaling, NF-kB Signaling, Immune Cell Signaling, Signaling Pathways Activating p38 MAP KinaseSTING Signaling, T cell receptor signaling, Inhibition of Apoptosis, Contribution of Soluble Factors to EMT,

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q04206

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only