NFX1 Polyclonal Antibody - BT-AP02229

NFX1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP02229-20, BT-AP02229-50, BT-AP02229-100

Citations, Manuals and MSDS Available upon request.

Background: MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes| two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants| each of which encodes a different isoform| have been identified.

Research Areas: Cell biology; Epigenetics and nuclear signaling; Immunology

Target Protein: NFX1

Applications: WB, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Transcriptional repressor NF-X1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q12986; Mouse: B1AY10

Synonyms: Transcriptional repressor NF-X1;EC 6.3.2.-;Nuclear transcription factor; X box-binding protein 1

GeneID: Human: 4799

Research Use Only