NGEP rabbit pAb - ES6477

NGEP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6477-50, ES6477-100

Citations, Manuals and MSDS Available upon request.

Background: This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011],

Alternate Name: ANO7; NGEP; PCANAP5; TMEM16G; Anoctamin-7; Dresden transmembrane protein of the prostate; D-TMPP; IPCA-5; New gene expressed in prostate; Prostate cancer-associated protein 5; Transmembrane protein 16G

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human TM16G. AA range:881-930

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 105kD

Human Gene ID: 50636

Human SWISS Prot NO: Q6IWH7

Subcellular Location: [Isoform 1]: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum. Concentrates at sites of cell-cell contact (PubMed:17308099). Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604.; [Isoform 2]: Cytoplasm, cytosol.

Research Use Only