NGFR p75 Rabbit Monoclonal Antibody-BS9819M

NGFR p75 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9819M-50, BS9819M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P08138

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IHC, IP,

All Applications: WB: 1:1000-1:5000
IHC/ICC/IF: 1:50-1:200
IP: 1:50-1:200

Background: NGFR p75 is a 75kD transmembrane glycoprotein (399 a.a.) consisting of an extracellular domain (222 a.a.) which contains four cysteine rich domains responsible for ligand binding, a transmembrane domain (22 a.a.), and a cytoplasmic domain (155 a.a.). NGFR p75 is mainly expressed in Schwann cells and neurons and in a variety of non neuronal cells. NGFR p75 is necessary for regulating neuronal growth, migration, differentiation and cell death during development of the central and peripheral nervous system.

Purification and Purity: Protein A affinity purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of NGFR p75 and does not cross-react with related proteins.

Bioworld Molecular Weight: ~ 45, 75 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of NGFR p75 Rabbit mAb at 1:1000 dilution
Lane 1: The skeletal muscle tissue lysate of Human, Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-NGFR p75 antibody. Counter stained with hematoxylin, ICC staining NGFR p75 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS

Alternative Name: Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271; NGFR; TNFRSF16

Immunogen: Recombinant antibody.

Conjugate: Unconjugated

Modification: Unmodified