Product Description

NGFRAP1 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8819-50, BS8819-100

Swiss-Prot: Q00994

Host: Rabbit

NGFRAP1 Polyclonal Antibody-BS8819

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: Bex3, also known as p75NTR-associated cell death executor (NADE), nerve growth factor receptor-associated protein 1 or ovarian granulosa cell 13 kDa protein HGR74, is a member of the Bex family involved in zinc-triggered neuronal cell death. It can be found in prostate, testis, liver, ovarian granulosa cells and seminal vesicle tissue shuttling between the cytoplasm and the nucleus. Bex3 interacts with Smac (second mitochondria-derived activator of caspase) via its C-terminal and regulates apoptosis by the inhibition of Smac ubiquitination. Bex3 also interacts with itself and the NGFR p75 DEATH domain. Bex3 may play a significant role in the pathogenosis of neurogenetic diseases.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: NGFRAP1 polyclonal antibody detects endogenous levels of NGFRAP1 protein.

Bioworld Molecular Weight: ~ 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using NGFRAP1 Antibody., Immunofluorescence analysis of MCF-7 cells using NGFRAP1 antibody.

Alternative Name: Protein BEX3; Brain-expressed X-linked protein 3; Nerve growth factor receptor-associated protein 1; Ovarian granulosa cell 13.0 kDa protein HGR74; p75NTR-associated cell death executor; NGFRAP1; BEX3, DXS6984E, NADE

Immunogen: Recombinant full length Human NGFRAP1.

Modification: Unmodified

Conjugate: Unconjugated