Product Description

NHERF-2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06018-20, BT-AP06018-50, BT-AP06018-100

Citations, Manuals and MSDS Available upon request.

Background: SLC9A3R2 (SLC9A3 regulator 2) encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator(CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SLC9A3R2.

Research Areas: Signal Transduction

Target Protein: SLC9A3R2

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: NHERF-2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 37414

UniProt Accession: Human: Q15599; Mouse: Q9JHL1; Rat: Q920G2

Synonyms: SLC9A3R2; NHERF2; Na(+)/H(+) exchange regulatory cofactor NHE-RF2; NHERF-2; NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; So

GeneID: Human: 9351; Mouse: 65962; Rat: 116501

Research Use Only