NHRF1 Polyclonal Antibody - BT-AP13945

NHRF1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP13945-20, BT-AP13945-50, BT-AP13945-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2| and loss of heterozygosity of this gene is implicated in breast cancer.

Research Areas: Signal transduction; Cancer; Tags and cell markers

Target Protein: SLC9A3R1

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Na

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O14745; Mouse: P70441; Rat: Q9JJ19

Synonyms: Na;+/H;+ exchange regulatory cofactor NHE-RF1;NHERF-1;Ezrin-radixin-moesin-binding phosphoprotein 50;EBP50;Regulatory cofactor of Na;+/H;+ exchanger;Sodium-hydrogen exchanger regulatory f

GeneID: Human: 9368

Research Use Only