Product Description

Nibrin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11362-50, MB11362-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: O60934

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 85 kDa; Observed MW: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of p95/NBS1 in Hela lysates using Nibrin antibody., Immunocytochemistry analysis of p95/NBS1 in MCF-7 using p95/NBS1 antibody, and DAPI

Alternative Name: NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1

Immunogen: A synthetic peptide of human p95 NBS1

Conjugate: Unconjugated

Modification: Unmodified