Product Description

Nibrin Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16581-50, BZ16581-100

Swiss-Prot: O60934

Host: Rabbit

Nibrin Polyclonal Antibody-BZ16581

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF, IP, , FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Background: NBS1 is a member of the MRE11/RAD50 double-strand break repair complex. Involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Mutation results in the Nijmegen breakage syndrome (NBS), an autosomal recessive chromosomal instability syndrome.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 85 kDa; Observed MW: 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of p95/NBS1 in HeLaLysates using Nibrin antibody., Immunohistochemistry analysis of paraffin-embedded rat heart using p95/NBS1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1

Immunogen: A synthesized peptide derived from human p95/NBS1

Modification: Unmodified

Conjugate: Unconjugated