Nicalin rabbit pAb - ES6862

Nicalin rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6862-50, ES6862-100

Citations, Manuals and MSDS Available upon request.

Background: function:May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning., similarity:Belongs to the nicastrin family., subunit:Interacts with NOMO2. Due to the strong similarity between NOMO1, NOMO2 and NOMO3, it probably also interacts with NOMO1 and NOMO3. Participates in a large protein complex, which is not related to the gamma-secretase complex., tissue specificity:Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart.,

Alternate Name: NCLN; Nicalin; Nicastrin-like protein

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human NCLN. AA range:474-523

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 63kD

Human Gene ID: 56926

Human SWISS Prot NO: Q969V3

Subcellular Location: Endoplasmic reticulum membrane; Single-pass membrane protein.

Research Use Only