Nicastrin Monoclonal Antibody-MB11308

Nicastrin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11308-50, MB11308-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q92542

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Nicastrin in K562, rat Brain, 3T3, HelaLysates using Nicastrin antibody.

Bioworld Molecular Weight: Calculated MW: 78 kDa; Observed MW: 110-120 kDa

Specificity: IgG

Alternative Name: APH2; Ncstn; NCT; Nicastrin

Immunogen: A synthetic peptide of human Nicastrin

Conjugate: Unconjugated

Modification: Unmodified