NIT1 Monoclonal Antibody-MB11310

NIT1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11310-50, MB11310-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q86X76

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of NIT1 in Hela, 293T, Jurkat, 3T3Lysates using NIT1 antibody.

Bioworld Molecular Weight: Calculated MW: 36 kDa; Observed MW: 36 kDa

Specificity: IgG

Alternative Name: Nitrilase homolog 1

Immunogen: A synthetic peptide of human NIT1

Conjugate: Unconjugated

Modification: Unmodified