Product Description

NKIRAS1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65546-50, BS65546-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Small guanosine triphosphatases, typified by the mammalian Ras proteins, play major roles in the regμlation of numerous cellμlar pathways. IκBinteracting Ras-like proteins, κB-Ras1 and κB-Ras2, belong to a subclass of evolutionarily conserved Ras-like proteins that differ from other Ras proteins in containing amino acids at positions 12 and 61 that are similar to those present in the oncogenic forms of Ras. These Ras-like proteins, κB-Ras1 and κB-Ras2, interact with the PEST domains of IκBa and IκBb and decrease their rate of degradation. κB-Ras2 shows 71% identity to κB-Ras1. In cells, κB-Ras proteins are associated only with NFκB:IκBb complexes and therefore may provide an explanation for the slower rate of degradation of IκBb compared with IκBa.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit

Host: Rabbit

Applications: WB

Alternate Names: 2400004O09Rik, I kappa B interacting Ras like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B Ras 1, Kappa B Ras protein 1, Kappa B-Ras protein 1, KappaB Ras1, KappaB-Ras1, KBRAS 1, KBRAS1, KBRS1_HUMAN, NF kappa B inhibitor interacting Ras like protein 1, NF-kappa-B inhibitor-interacting Ras-like protein 1, NFKB inhibitor interacting Ras like 1, NFKB inhibitor interacting Ras like protein 1, NKIRAS 1, nkiras1.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human NKIRAS1:131-192/192

Dilution: WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations shoμld be determined by the end user.

Purification: affinity purified by Protein A

Specificity: NKIRAS1 polyclonal Antibody detects endogenous levels of NKIRAS1 protein.

Molecular Weight: ~22kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NYS0

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only