Product Description

NKRF Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4030-25, MB4030-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: NF-κB Repressing Factor (NKRF) is a constitutively expressed transcription factor that binds to the negative regμlatory element within the promotor region of many genes that are transactivated by NF-κB (1). Indeed, research studies have found NKRF to repress transcription of IL-8/CXCL8, iNOS, CXCL10, and IFN-γ (2-4). In addition to regμlating the expression of pro-inflammatory factors, NKRF has been shown to play a role in cell survival in the context of proteotoxic stress, through the regμlation of rRNA processing and ribosome biogenesis (5).

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: WB

Alternate Names: NF-kappa-B-repressing factor, NFkB-repressing factor, Protein ITBA4, NKRF, ITBA4, NRF, 9606 NCBIHomo sapiens (Human)

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Human recombinant protein fragment corresponding to amino acids 1-296 of human NKRF(NP_060014) produced in E.coli.

Dilution: WB 1:2000

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG2a

Molecular Weight: ~ 90 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O15226

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only