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NKX2-5 Polyclonal Antibody - E-AB-68374

NKX2-5 Polyclonal Antibody - E-AB-68374

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NKX2-5 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-68374-60, E-AB-68374-120, E-AB-68374-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NKX2-5

Target Synonym: NKX2-5; CHNG5; CSX; CSX1; HLHS2; NKX2.5; NKX2E; NKX4-1; VSD3

Research Areas: Cancer, Cardiovascular, Developmental Biology, Neuroscience, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P52952

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human NKX2-5

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 11kDa/16kDa/34kDa

Observed MW: 37kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only